Resolute® BioSMB Platform

Single-Use Multi-Column Chromatography

Resolute® BioSMB PD and BioSMB 80|350 chromatography systems are designed to purify biologics from process development to commercial manufacturing scale.

  • Easily scalable single-use platform
  • Harmonized good manufacturing practice (GMP)-ready software across the entire Resolute® BioSMB platform
  • Up to 80% reduction in resin volumes and costs

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The Resolute® BioSMB PD and BioSMB 80|350 systems are multi-column chromatography systems designed to increase the efficiency and productivity of fed-batch, intensified fed-batch, and perfusion processes during chromatography unit operations. Multi-column chromatography (MCC) using Resolute® BioSMB reduces resin usage by up to 80% without impacting critical chromatography processes. This presents a significant saving on operational expenditure, particularly when considering affinity capture steps.

Applications

  • Application
    • mAB Production
    • Antibody Purification
    • Polishing
    • Capture
    • Affinity
    • Large Molecules
  • Application Area
    • Process development
    • Clinical manufacturing
    • Commercial manufacturing

Product Information

  • Brand
    Resolute®
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