CM Ceramic HyperD® F
CM Ceramic HyperD® is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.
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CM Ceramic HyperD® F ion exchange chromatography resin is designed using proprietary 'gel-in-a-shell' design that provides rapid mass transfer and effective binding. It relies on a high capacity hydrogel, polymerized within the gigapores of a rigid ceramic bead.
Features and Benefits
- High dynamic binding capacity at high flow rates
- Truly rigid, non-compressible resin
- Salt tolerant CM Ceramic HyperD™ F resin reduces Ultrafiltration/Diafiltration (UF/DF) requirements
Applications
- Recombinant proteins
- Purification of enzymes, plasma proteins
- Vaccines
- Direct capture of monoclonal antibodies
- IgM
Compliance Information
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Quality Standards
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CoA
- RSF
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CoA
Dimensions
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Bead Size50 µm
Materials of Construction
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Base MatrixCeramic Beads
Operating Conditions
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Operating Pressure< 3 barg (44psi)
Physicochemical Information
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LigandCarboxymethyl
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Ligand Density250-400 µeq/mL
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Reference ProteinHuman polyclonal IgG
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Typical Dynamic Binding Capacity 10% per mL> 60 mg/mL hIgG
Product Information
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BrandCM Ceramic HyperD®
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Resin TypeWeak cation exchanger
Storage Conditions
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Storage Conditions20% EtOH/1M NaCl