Sartoguard PES | Cartridge | 0.2µm | 20"

The asymmetric polyether sulfone (PES) membranes used in Sartoguard PES filters achieve an LRV of 6 per cm². This significantly reduces the bioburden in the downstream process and protects subsequent purification steps. When used upstream of sterilization grade filters, Sartoguard PES increases overall throughput and reduces the number of filters required and process costs.

Main Applications

• Bioburden reduction in protein- and virus-based therapies as well as in processes producing pDNA/mRNA based therapies
• Protection of purification equipment and sterilizing-grade filters

Benefits

• More economical process flow
• Downsizing of filtration systems
• Significantly higher total throughput performance
• LRV of 6 per cm2 filtration area for Brevundimonas Diminuta (0.1 µm version) and for Serratia Marcescens (0.2 µm version)

Membrane

Sartoguard PES uses a heterogeneous double membrane made of polyethersulfone

Compatibility

Sartoguard PES filter cartridges have been developed for sterilization using either autoclaving or in-line-steaming. The polyethersulfone membrane used is suitable for the filtration of liquids in the pH range of pH 1-14.

Flexibility

Sartoguard PES filters are available in a wide range of filtration areas from 4.5 cm² up to 1.8 m² and with a variety of commonly used connections to ensure easy integration into your process regardless of batch size.

Scale Up:

Consistent and predictable scale-up and scale-down procedures can be safely performed because all Sartoguard PES filter elements are manufactured with the same membrane type, support fleeces and construction materials.

Quality:

Every single element is tested for integrity to meet the highest quality requirements.

Documentation:

Sartoguard PES filters have been designed, developed and produced in accordance with the ISO 9001 certified quality management system. A validation manual is available in accordance with regulatory requirements.