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CM Ceramic HyperD® F is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.

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CM Ceramic HyperD® F
CM Ceramic HyperD® F

CM Ceramic HyperD® F is a weak cation exchanger for biomolecule purification. Changes in conductivity and pH can optimize purification steps by utilizing the charge change on protein and ligand.

Item No.:
M_CM_Ceramic_HyperD

Overview

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CM Ceramic HyperD® F ion exchange chromatography resin is designed using proprietary gel-in-a-shell design that provides rapid mass transfer and effective binding. It relies on a high capacity hydrogel, polymerized within the gigapores of a rigid ceramic bead. This salt-tolerant resin reduces Ultrafiltration (UF) and Diafiltration (DF) requirements, enhancing process efficiency.

Features and Benefits

  • High dynamic binding capacity at high flow rates
  • Truly rigid, non-compressible resin
  • Salt tolerant CM Ceramic HyperD® F resin reduces Ultrafiltration/Diafiltration (UF/DF) requirements

Applications

  • Recombinant proteins
  • Purification of enzymes, plasma proteins
  • Vaccines
  • Direct capture of monoclonal antibodies
  • IgM

Compliance Information

  • Quality Standards
    • CoA
    • RSF (upon request)

Dimensions

  • Bead Size
    50 µm

Materials of Construction

  • Base Matrix
    Ceramic Beads

Operating Conditions

  • Operating Pressure
    < 3 barg (44psi)

Physicochemical Information

  • Ligand
    Carboxymethyl
  • Ligand Density
    250-400 µeq/mL
  • Reference Protein
    Human polyclonal IgG
  • Typical Dynamic Binding Capacity 10% per mL
    > 110 g/L

Product Information

  • Brand
    CM Ceramic HyperD®
  • Resin Type
    Weak cation exchanger

Storage Conditions

  • Storage Conditions
    1M NaCl with 20% EtOH, 1.2 mM EDTA