Flexsafe® RM 50L perfusion (3 pcs)
The Flexsafe® RM single-use bioreactor bags (sizes from 2 L to 200 L) fit to the Biostat® RM bioreactors. The product is based on rocking motion mixing technology which is ideal for cell cultivation with low shear stress.
Perfusion bags are available in two versions:
A) With an integrated 1.2 μm perfusion membrane (PES). The membrane is fixed at the bottom of the bag, forming a compartment for removal of cell free media. The wave created by the agitation moves over the surface of the membrane, thereby flushing the membrane with every rocking motion. This innovative and patented design ensures low fouling and long cultivation times.
B) ATF perfusion bags are designed for convenient connection.
- Item No.:
- DFP050L--SM
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your Flexsafe® RM
- Integrates single-use pH and DO sensors
- Excellent cell growth and robustness
- Integrated BioPAT® Viamass sensor for viable biomass measurement
- Customized bag designs possible
- Delivered gamma-irradiated and ready to use
The optical bag is mainly used for an advanced applications. It can also be scaled up to our Biostat STR® single-use stirred tank bioreactor equipped with Flexsafe STR® bags. Flexsafe® RM bags are proven for a broad range of different cell lines incl. CHO, NS0, SF9, E.coli and mesenchymal stem cells. They are available in six different sizes supporting working volumes from 200 mL up to 100 L. Standard designs are available from stock.
Applications
-
Application
-
Mammalian cell culture
-
Insect cell culture
-
Microbial Fermentation
-
Low molecular weight binding
- Shear-stress-sensitive cells such as stem cells
-
Mammalian cell culture
-
Application AreaPreclinical and clinical studies
Compliance Information
-
Biocompatibility (USP Class VI)
-
USP Class VI and | or ISO 10993 conformity
-
USP <85>
-
USP <87> | ISO 10993-5
-
USP <88>
- USP <788>
-
USP Class VI and | or ISO 10993 conformity
Components
-
Gas FiltersHEPA rated hydrophobic filter
Connections (Physical)
-
Connector(s)
-
Female | Male Luer
-
Female | Male MPC
-
Clave® connector
- Opta® SFT Connector
-
Female | Male Luer
Features
-
Device/Instrument CompatibilityBiostat® RM 20 | 50 L
-
Sensors
-
Optical DO
- Optical pH
-
Optical DO
General Specifications
-
pH RangepH 6.0 – 8.0
Materials of Construction
-
Film MaterialS80
-
MembranePolyethersulfone (PES) 1.2 μm
Operating Conditions
-
Operating Conditions - Temperature16 – 40°C (specified by the hardware)
Physicochemical Information
-
Pressure RangeOperation pressure: 6 mbar [g] - 30 mbar [g]
Product Information
-
BrandFlexsafe® RM
Usage Protocols
-
Gamma Irradiation≥25 kGy
Volume
-
Working Volume5 – 25L