Sartobran® P | Maxicaps® | 0.45µm | 20"

Sartobran P 0.45 µm for Bioburden Reduction

Sartobran® P 0.45 µm filters provide bioburden and defined particle reduction for biopharmaceutical solutions, especially in vaccine and blood and plasma processes. The cellulose acetate membrane enables very low unspecific adsorption to support high product recovery and efficient processing.

Key Features

• Cellulose Acetate Membrane: Very low unspecific adsorption supports high recovery of proteins and excipients, helping protect product yield.
• Bioburden and Particle Reduction: Applied upstream to protect sterilizing-grade membrane filters and downstream equipment, improving process robustness.
• Linear Scale-Up: Filtration areas from 4.5 cm² to 1.8 m² across different formats enable straightforward scaling from PD to production.
• pH Compatibility: Operates within pH 4–8, covering a large portion of bioprocess fluids used in typical formulations.
• Integrity and Compliance: Each element is integrity tested by bubble point and diffusion methods and manufactured under an ISO 9001 certified Quality Management System.
• Sterilization Flexibility: Autoclavable and in-line steam sterilizable options (by format), with gamma-irradiatable variants available, support integration into existing SOPs.
  

Applications

• Coagulation Factors, Albumin, IgG
• Bacterial and Viral Vaccines
• Bioprocessed pharmaceuticals
• Intermediate and purified protein solutions
• Biological fluids
• Fluids containing preservatives
  

Benefits

• High Product Recovery: Very low unspecific adsorption limits product binding and supports high yield in vaccine, plasma, and protein processes.
• Efficient Processing: High throughput and reliable flow performance help shorten filtration cycles and streamline operations.
• Downstream Protection: Upstream bioburden reduction helps protect sterilizing-grade filters and equipment, supporting consistent performance.
• PFAS: Made without intentionally using PFAS compounds.