BioPAT® Spectro Raman

BioPAT^® Spectro in Ambr^® 15 and Ambr^® 250 high throughput reduces model building time by 50%, can result in up to a 95% reduction in operator involvement and up to 80% savings in media costs when compared to conventional model building (assumption). BioPAT^® Spectro enables a QbD approach in high-throughput process development, measuring several analytes simultaneously during Design of Experiments (DoE). It offers fully automated data consolidation and contextualization of Raman spectral data with all process data by Ambr^® software. After one high throughput Ambr^® run, the consolidated date file can be readily imported into SIMCA^® , where the larger design space means more robust models than formerly possible.

The BioPAT^® Spectro single-use port is fully integrated into Flexsafe STR^® bags. BioPAT^® Spectro is a scalable platform with standardized optical probe interface across Ambr^® and Flexsafe STR^® facilitates model transfer. The fully integrated and qualified single-use port reduces set-up time and decreases contamination risks. The use of a flow cell in the design decouples the measurement from disturbances trough process conditions such as gassing and stirring. The shielded design of the measurement path eliminates noise through ambient light.