Sartobran® P with its unique cellulose acetate (CA) membrane is mainly used for the sterile filtration of blood & plasma products as well as viral vaccines. The ultra-low binding feature of the membrane material leads to highest product yield. Especially large, shear-stress sensitive proteins do not lose their structure and function when filtered through this special membrane. This will improve your process output even further.

Item No.: 
5232507H2----P

*Custom/bulk order quotes are provided within 72 hours of request.

Sterilizing-Grade, 0.2 µm Rated Filters

Sartobran® P Pore size: 0.45 | 0.2 µm (CA double layer)

Your Benefits

  • High product yield due to ultra-low unspecific adsorption
  • Excellent filtration results especially for large, shear-stress sensitive proteins
  • Ideally suited for sterile filtration of viral vaccines and blood & plasma products

Sartobran® P filters are not suitable for gamma irradiation. For easy integration of non-gamma filters into single-use assemblies, we offer a wide range of possibilities with our Filter Transfer Set solutions.

For highest process flexibility Sartobran® P filters are available for conventional stainless-steel or single-use applications. The filter elements are available in various sizes and connector combinations. Please review the selection guide in the supporting literature.

Applications

  • Application
    • Blood and Plasma  
    • Vaccine Production  

Biological Information

  • Bacterial Retention
    Quantitative Retention of 1 × E7 CFU/cm² Brevundimonas Diminuta ATCC® 19146 per ASTM methodology  

Compliance Information

  • Bacterial Endotoxins
    < 0.25 EU/mL as determined by the LAL test  
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).  
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".  

Connections (Physical)

  • Connector Inlet
    2-Flange Bayonet Adapter with 226 Double O-ring (25)  
  • Connector Outlet
    2-Flange Bayonet Adapter with 226 Double O-ring (25)  

Dimensions

  • Filter Size
    20"(1.2 m² / 12.9 ft²)  
  • Filtration Area
    1.2 m² / 12.9 ft²  
  • Outer Diameter
    70 mm  

General Specifications

  • Capsule/Cartridge Format
    Cartridges  
  • Maximum Allowable Back Pressure
    2 bar (29 psi) at 20°C; 1 bar (14.5 psi) at 80°C  
  • Maximum Diffusion
    30 mL/min at 2.5 bar | 36 psi  
  • Minimum Required Bubble Point
    3.2 bar | 46 psi  
  • Vent Valve
    N/A  

Materials of Construction

  • Filter Material
    Cellulose Acetate (CA)  
  • Housing Material
    Polypropylene (PP)  
  • Material o-ring | seal
    Silicone (SI)  
  • Support Fleece
    Polypropylene (PP)  

Operating Conditions

  • Maximum Differential Pressure
    20 °C: 5 bar; 80 °C: 2 bar  
  • Maximum Operating Pressure
    5 bar (72.5 psi)  

Physicochemical Information

  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.  
  • Pore Size Final-filter
    0.2 µm  
  • Pore Size Pre-filter
    0.45 µm  

Product Information

  • Brand
    Sartobran®  

Sterility/Purity

  • Sterilization Method
    Autoclavable & In-Line Steam Sterilizable  

Usage Protocols

  • Sterilization Procedures
    • In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles  
    • Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles  
  • Liquid Filter Housings
    Item no.
    M_Liquid_Filter_Housings

    Sartorius Stedim Biotech Sanitary Single Round Filter Housings are specifically designed for liquid filtration applications of the Bio-Pharmaceutical Industry. Application: bioreactors, CIP skids, autoclaves, lyophilizers and process tanks.

  • Sartocheck® 5 Plus Filter Tester
    Item no.
    26787---FT---P

    The Sartocheck® 5 Plus Filter Tester is an automatic filter integrity tester with automated Quality Risk Management (QRM) designed to cover the complete range of integrity testing from small syringe filters up to large multi-round housings and tangential flow cassettes.

  • Sartocheck® 5 Filter Tester
    Item no.
    26787---FT

    The Sartocheck® 5 Filter Tester is an automatic filter integrity tester designed to cover the complete range of integrity testing from small syringe filters up to large multiround housings and tangential flow cassettes.

  • Sartoclean®
    Item no.
    M_Sartoclean

    Sartoclean® family is a cellulose acetate (CA) membrane based prefilter. These filters are optimized for the protection of downstream equipment and Sartobran® cellulose acetate final filters.