Sartoclean®

Sartoclean CA and GF Prefilters

Sartoclean® CA and Sartoclean® GF prefilters prepare biopharmaceutical liquids for critical steps by combining clarification and bioburden reduction. Low adsorption and high loading capacity support consistent flow, high recovery, and efficient processing from PD to production.

Key Features

• Double-Layer Cellulose Acetate (CA): Two cellulose acetate layers increase particle loading capacity and throughput, reducing changeouts and helping maintain stable flow in protein-rich solutions.
• Glass Fiber Adsorptive Design (GF): two cellulose acetate membranes combined with glass fiber fleece captures colloids and lipids, improving clarification and supporting lower turbidity.
• High Throughput Performance: Optimized constructions manage particulate and colloid loads effectively, which helps shorten filtration cycles and improve line utilization.
• Robust Operation Up To 5 bar: Mechanical and thermal resilience support demanding unit operations, providing dependable performance at elevated differential pressures.
• Scalable Portfolio: Various formats all offering aligned materials and membrane architectures for predictable scale-up and streamlined qualification.
  

Applications

• Sartoclean® CA: Plasma fractions | Vaccines | mAb | Diagnostics | Purified protein solutions | Biological fluids | Solutions containing preservatives.
• Sartoclean® GF: Fermentation broths | Serum | Plasma | Cell culture media | Colloid and lipid containing solutions.
  

Benefits

• High Product Recovery: Very low non-specific adsorption of cellulose acetate helps minimize product loss and supports yield.
• Strong Clarification and Bioburden Control: GF adsorptive fleece and CA double layers reduce particulates, colloids, and microbial load, supporting consistent upstream and intermediate steps.
• Fewer Filter Changeouts: Elevated particle loading capacity and high throughput enable longer runs between replacements, which can reduce process time and labor.
• Stable, Predictable Flow: Effective removal of fouling species helps keep differential pressure growth under control, supporting steady performance and downstream reliability.
• PFAS: Made without intentionally using PFAS compounds.