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Full Flexibility Meets Outstanding TFF Performance

Flexible solution

0.1 - 2.1 m² membrane sizes | 10 L stainless steel vessel or 5, 10, 20 L single-use bags for recirculation

High product yields

4-piston membrane pump for low shear

Highly automated

Two pumps for feed and buffer addition, as well as full TMP control

Item No.: 
SFADVANCED
Piece
1
*Custom/bulk order quotes are provided within 72 hours of request.
Sartoflow® Advanced
Sartoflow® Advanced

Full Flexibility Meets Outstanding TFF Performance

Flexible solution

0.1 - 2.1 m² membrane sizes | 10 L stainless steel vessel or 5, 10, 20 L single-use bags for recirculation

High product yields

4-piston membrane pump for low shear

Highly automated

Two pumps for feed and buffer addition, as well as full TMP control

Item No.:
SFADVANCED
Number of pieces
1

Overview

Specifications

Application & Configuration

The Sartoflow® Advanced is a modular crossflow system for ultrafiltration, microfiltration and diafiltration applications in many biopharmaceutical processes, such as the purification of vaccines, monoclonal antibodies and recombinant proteins. The Sartoflow® Advanced can also be used under demanding laboratory and production conditions.

TFF Cassettes for the Sartoflow® Advanced

Sartocon® Slice with 0.1 m² membrane area

  • Hydrosart® UF membrane - MWCO 2, 5, 10, 30, 100 kD
  • PESU UF membrane - MWCO 1, 5, 8, 10, 30, 50, 100, 300 kD and Albumin
  • Hydrosart® MF membrane - MWCO 0.2 and 0.45 μm
  • PESU MF membrane - MWCO 0.1 μm

Sartocon® Slice with 0.14 - 0.7 m² membrane area

  • Hydrosart® membrane - MWCO 10, 30, 100 kD

Applications

  • Application
    • Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
    • Ultrafiltration
    • Diafiltration
    • Microfiltration

Connections (Physical)

  • Connector(s)
    0.5" Tri-clamp

Dimensions

  • Dimensions WxDxH
    1,100 × 800 × 680 mm
  • Membrane Area
    0.1 - 0.5 m² (optionally 0.7 - 2.1 m²)
  • Tube Size (ID – OD)
    1/2"

Features

  • Display
    Yes
  • Display Size
    12" (800 x 600 pixel)
  • Sensors
    • Pressure
    • Flow
    • Temperature

General Specifications

  • Cassette Format
    • Sartocon Cassettes
    • Slice Cassettes
    • Standard Cassettes
  • Filter Format
    Cassettes
  • Pump Output
    700 L/h @ 4 bar (60 psi)
  • Surface Roughness of Wetted Parts
    Ra <= 0.6 µm

Materials of Construction

  • Recirculation Vessel
    Stainless steel 316 L

Operating Conditions

  • Maximum Operating Pressure
    4 bar (60 psi)
  • Minimum Operating Volume
    ~200 mL

Power Requirements

  • Power Requirements
    230 VAC | 50 Hz 2.5 Amp;120 VAC | 60 Hz 4 Amp

Product Information

  • Brand
    Sartoflow®

Volume

  • Bag Volume
    5, 10, 20 L (SU)
  • Hold-up Volume
    200 mL
  • Recirculation Vessel Volume
    10 L (MU)

Weight

  • Total Weight
    ~ 120 kg (~265 lbs.)

Questions & Answers (4)

Options include stainless steel tanks or single-use bags, both designed to prevent foaming and ensure efficient recirculation.