Sartopore® 2 XLG Sartoscale 47 | 3pc.

  • Effective Filtration Area: 17.3 cm²
  • Pore Size: 0.8 µm prefilter | 0.2 µm final filter
  • Connectors: Inlet: Sanitary ¾“| Outlet: Sanitary ¾“
  • Membrane Material: Polyethersulfone
  • Pack Size: 3 pieces

Type
Price (USD):
$91.20
Item No.: 
5445307GS--FF--M

*Custom/bulk order quotes are provided within 72 hours of request.

Sartopore® 2 XLG Sartoscale filters are single-use screening tools used in process development and optimization to find the optimal filtration set-up for a biomanufacturing process. They contain the same filter materials as their process filter counterparts to assure data consistency for scale-up.

Sartopore® 2 XLG is a high-performance membrane filter, offering more than just reliable sterilizing-grade filtration in biopharmaceutical processes. Its highly asymmetric membrane structure and composition of 0.8µm prefilter in front of the sterilizing-grade filter (0.2 µm pore size), boosts the filtration efficiency in downstream processing of protein-based therapies or innovative drug delivery systems like lipid nanoparticles (LNPs). Thanks to the outstanding total throughput, Sartopore® 2 XLG is also a choice for filtration after the cell harvest.

The XL in its name indicates an increased effective filtration area (EFA). By using a different pleating technology, the EFAs of Sartopore ® 2 XLG filters are - depending on filter format - 30-40% higher than for the conventional Sartopore® 2 filters. This leads to higher total throughput per filter element and less filter consumption or enables the use of a smaller filter element for a process to reduce the footprint and waste.

Sartopore® 2 XLG filters are available in all established formats with different sizes and for different purposes: Conventional filter cartridges for stainless steel housings or single-use capsules like the small Capsules, the mid-sized Midicaps®, the larger Maxicaps® / T-Style Maxicaps® and the Maxicaps® MR for very large volumes (e.g, clarification after bioreactor harvest). The single-use capsules are available as pre-sterilized (by autoclaving), autoclavable or gamma irradiatable versions. The wide range of different filter formats and sizes ensures that customers can easily scale up their process during drug development process – from preclinical to commercial scale.

Focus Applications

  • Cell culture media preparation
  • Post cell harvest filtration
  • Protein-based therapies (Downstream intermediates, form & fill)
  • Lipid nanoparticles (Downstream intermediates, form & fill)

Your Benefits

  • Increased total throughput leads to less filter consumption, less process interruptions and reduced costs
  • Increased effective filtration enables the use of smaller filters to reduce footprint and waste
  • Proven and robust membrane chemistry known from the widely established Sartopore® 2 family lowers validation effort in case of process optimization
  • Broad range of formats and sizes assures scalability and enables use of Sartopore® 2 XLG along the whole drug product lifecycle: from development to commercial processes
  • Offers secure bacterial retention according to ASTM guidelines

Applications

  • Industry
    Pharma / Biotech  

Compliance Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test  
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).  
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".  

Connections (Physical)

  • Connector Inlet
    3/4" Sanitary  
  • Connector Outlet
    3/4" Sanitary  

Dimensions

  • Filter Size
    17.3 cm²  
  • Filtration Area
    17.3 cm²  

General Specifications

  • Capsule/Cartridge Format
    Sartoscale 47  
  • Minimum Required Bubble Point
    3.2 bar | 46 psi  

Materials of Construction

  • Housing Material
    Polypropylene (PP)  
  • Membrane Material
    Polyethersulfone (PES)  

Operating Conditions

  • Maximum Differential Pressure
    20 °C: 5 bar, 80 °C: 2 bar  

Physicochemical Information

  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.  
  • Pore Size Final-filter
    0.2 µm  
  • Pore Size Pre-filter
    0.8 µm  

Product Information

  • Brand
    Sartopore® 2  
  • Pack Size
    3  
  • Type
    Sartoscale 47 | Connectors: Sanitary | 3 pc.  

Usage Protocols

  • Sterilization Procedures
    Autoclaving: 1 cycle at max. 134 °C, 2 bar | 29 psi, 30 min.