Vivaspin® 2 Centrifugal Concentrator Hydrosart®, 25 pc

Top Features

  • Avoids membrane fouling with crossflow technology for low-volume samples
  • Increases process speeds with high flux design and membranes
  • Adapts to your sample needs for concentration and diafiltration of almost any macromolecule
  • Retentate sample retrieval with or without a pipette

Popular Applications 

  • Concentration  
  • Desalting  
  • Buffer exchange 
  • Cell removal/harvest  

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Vivaspin® centrifugal concentrators are disposable ultrafiltration units for the concentration of most macromolecules – including proteins, viruses, nucleic acids and nanoparticles – thanks to a broad range of molecular weight cut-offs (MWCO) and membrane materials.

Vivaspin® 2 is recommended for concentration or diafiltration of initial sample volumes up to 3 mL. It features a vertical membrane for high-speed filtration, with volume graduations on the housing to allow easy monitoring of ultrafiltration progress. Vivaspin® 2 combines the speed of the original Vivaspin® products with low internal surface and membrane areas, and a choice between polyethersulfone (PES), Hydrosart® regenerated cellulose (HY/RC) or cellulose triacetate (CTA) materials, to ensure superior recoveries of any target molecule, especially from very dilute samples. The integral dead-stop pocket enables more than 100-fold concentration factors while eliminating the risk of sample loss and simplifying retentate retrieval. Optionally, the concentrator can simply be inverted for pipette-free collection of the entire retentate sample into the included collection tube.

Application Notes






User Manual


  • Application
    • Concentration
    • Diafiltration
    • Desalting
    • Buffer Exchange
  • Industry
    Pharma / Biotech
  • Intended Use
    General Laboratory Use (GLU)
  • Market
    • Research
    • Environmental

Compliance Information

  • Animal Components
  • Certification
    ISO 9001


  • Membrane Area
    1.2 cm²
  • Overall Length
    126 mm

Materials of Construction

  • Concentrator Body/Sleeve
    Polycarbonate (PC)
  • Concentrator Cap
    Polycarbonate (PC)
  • Filtrate Vessel
    Polycarbonate (PC)
  • Membrane Material
    Hydrosart® (HY)

Physicochemical Information

  • MWCO
    10 kDa

Product Information

  • Brand
  • Device Type
  • Pack Size
  • Sample Type
    • Macromolecule
    • Protein
    • Peptide
    • Nanoparticles
    • Virus
    • VLP
    • Viral Vector
    • Exosome
    • LNP
    • Nucleic Acid


  • Dead Stop Volume
    8 µL
  • Hold-up Volume
    < 10 µL
  • Maximum Capacity, Fixed Angle Rotor
    2 mL
  • Maximum Capacity, Swing Bucket Rotor
    3 mL
  • Minimum Recirculation Volume
  • Volume Range
    0.4 – 3 mL

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