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- Sartobran® P | Capsule | 0.2µm | Size 4 | 5pc.
Sartobran® P | Capsule | 0.2µm | Size 4 | 5pc.
Sartobran® P 0.2 and 0.45 µm filters feature cellulose acetate membranes for low adsorption and high product recovery. The 0.2 µm grade ensures sterilizing filtration, while the 0.45 µm grade excels in bioburden reduction. Scalable formats support diverse biopharmaceutical applications.
- Price (USD)
- $314.00
- Item No.:
- 5231307H4--SS--B
- Pieces
- 5
Sartobran® P 0.2 and 0.45 µm filters feature cellulose acetate membranes for low adsorption and high product recovery. The 0.2 µm grade ensures sterilizing filtration, while the 0.45 µm grade excels in bioburden reduction. Scalable formats support diverse biopharmaceutical applications.
Overview
Specifications
Choose your Sartobran® P
Sartobran® P 0.2 and 0.45 µm filters
Sartobran® P filters combine cellulose acetate membranes with low adsorption to support high product recovery across vaccine, blood and plasma, and biopharmaceutical processes.
Key Features
- Low-Adsorption Membrane: Cellulose acetate minimizes unspecific binding to help protect yield and support consistent recovery of valuable proteins and excipients.
- Gentle To Proteins: Flow characteristics and membrane properties help maintain the structure of large, shear‑sensitive proteins for reliable process performance.
- Two Retention Ratings: 0.2 µm for sterilizing-grade filtration and 0.45 µm for bioburden and particle reduction, enabling step-appropriate selection in upstream and final steps.
- Scalable Portfolio: Sartoscales, Capsules, Midicaps®, Maxicaps®, and cartridges provide a common platform that supports linear scale-up from process development to commercial production.
- Process Compatibility: Operates in the pH 4–8 range typical for many formulation buffers and process fluids, broadening applicability across unit operations.
Applications
- Coagulation Factors, Albumin, IgG
- Bacterial and Viral Vaccines
- Bioprocessed pharmaceuticals
- Intermediate and purified protein solutions
- Biological fluids
- Fluids containing preservatives
Benefits
- High Product Recovery: Very low unspecific adsorption helps reduce product loss, supporting high yields in vaccines, blood and plasma, and biopharmaceutical processes.
- Consistent Sterile Performance: The 0.2 µm grade is validated as sterilizing-grade and supports reliable bacterial retention in critical steps.
- Efficient Bioburden Reduction: The 0.45 µm grade reduces bioburden and particles upstream to help protect final sterilizing filters and downstream equipment.
- PFAS: Made without intentionally using PFAS compounds.
Applications
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Application
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Blood and Plasma
- Vaccine Production
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Blood and Plasma
-
Modality
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Harvest | Cell Removal
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Downstream Intermediates
- Form & Fill
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Harvest | Cell Removal
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ScaleProduct Development | Scale Up Filters
Biological Information
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Bacterial RetentionQuantitative Retention of 1 × E7 CFU/cm² Brevundimonas Diminuta ATCC® 19146 per ASTM methodology
Compliance Information
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Bacterial Endotoxins< 0.25 EU/mL as determined by the LAL test
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Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
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ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Connections (Physical)
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Connector Inlet3/4" Tri-clamp 25 mm
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Connector Outlet3/4" Tri-clamp 25 mm
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Connector(s)Inlet: ¾" Sanitary | Outlet: ¾" Sanitary
Dimensions
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Filter Sizesize 4 (0.015 m² / 0.16 ft²)
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Filtration Area0.015 m² / 0.16 ft²
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Outer Diameter63 mm (46 mm without Connection / Valves)
General Specifications
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Capsule/Cartridge FormatCapsules
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Maximum Allowable Back Pressure2 bar (29 psi) at 20°C; 1.5 bar (21.8 psi) at 50°C
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Maximum Diffusion1 mL/min at 2.5 bar | 36 psi
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Minimum Required Bubble Point3.2 bar | 46 psi
Materials of Construction
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Filter MaterialCellulose Acetate (CA)
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Housing MaterialPolypropylene (PP)
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Material o-ring | sealSilicone (SI)
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Membrane MaterialCellulose Acetate (CA)
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Support FleecePolypropylene (PP)
Operating Conditions
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Maximum Differential Pressure20 °C: 4 bar, 50 °C: 2 bar
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Maximum Operating Pressure4 bar (58 psi)
Physicochemical Information
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Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
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Pore Size Final-filter0.2 µm
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Pore Size Pre-filter0.45 µm
Product Information
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BrandSartobran® P
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Pack Size5
Sterility/Purity
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Delivery ConditionSterile - Autoclaved
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Sterilization MethodAutoclavable
Usage Protocols
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Sterilization ProceduresAutoclaving: at 134°C, 30 min, 2 bar, min. 5 Cycles