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- Sartopore® Platinum | 0.2µm | Capsule (PD | Scale Up)
Sartopore® Platinum | Gamma Capsule | 0.2µm | Size 4 | 5pc.
Designed for scale-up in the PD area, Sartopore® Platinum Capsules offer high product yield with patented hydrophilization, ensuring low protein binding and reliable performance in process development.
- Item No.:
- 5491307H4G-OO--B
- Pieces
- 5
Designed for scale-up in the PD area, Sartopore® Platinum Capsules offer high product yield with patented hydrophilization, ensuring low protein binding and reliable performance in process development.
Overview
Specifications
Choose your Sartopore® Platinum
Sartopore® Platinum and Platinum HB Filters: Advanced Filtration Solutions
Sartopore® Platinum sterilizing-grade filters combine low adsorption and rapid wetting to support high product yield and fast setup in biotech workflows. Sartopore® Platinum HB adds a higher bubble points for demanding processes.
Key Features
- Patented Hydrophilization: Permanent surface modification of the PES membrane delivers high wettability and low protein adsorption, reducing flushing needs and helping protect product yield.
- Up To 95% Less Water: Excellent wettability cuts flushing volumes, enabling smaller waste bags and faster setup, especially beneficial for single-use assemblies.
- Elevated Bubble Point: The Sartopore® Platinum HB has a bubble point of at least 4.1 bar, which supports process robustness in challenging conditions and during long or start-stop filtration periods.
- Twinpleat Filtration Area Utilization: Increases effective filtration area per element and reduces footprint, improving throughput without enlarging assemblies.
Applications
In common
- Production of high-value biologicals like monoclonal antibodies
- Final conjugated bulk
- Point of fill filtration
Sartopore® Platinum
- Blood and plasma processes
- Ophthalmics
Sartopore® Platinum HB
- Processes with long filtration periods
- Processes with frequent start-stop
- Extremely challenging media (surfactant-containing | liposomal | lipid & lipid-like | protein-based)
Benefits
- Reduced Flushing And Water Use: Up to 95% less water minimizes disposal and simplifies single-use handling, supporting faster changeovers and lower utilities.
- Yield Protection: Low protein adsorption helps maintain product recovery for high-value biologics and sensitive formulations.
- Reliable Integrity Testing: Rapid wetting supports consistent integrity tests, reducing retesting effort and downtime in single-use workflows.
- Robust Performance In Challenging Media: Elevated bubble point (HB) and increased effective area help manage surfactant-containing, lipid-like, and protein-based media, and long filtration runs.
- Efficient Scale-Up: Broad format range enables linear transitions from PD to commercial scale in the range of 4.5 cm² up to 3 m², reducing filter count and optimizing footprint.
Sartopore® Platinum and Platinum HB filters offer advanced filtration technology with low adsorption and enhanced hydrophilicity, ensuring high product yield and efficient single-use processes across diverse applications. With their robust design, scalability, and compliance with industry standards, these filters provide significant benefits in terms of process efficiency, cost savings, and product safety.
Applications
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ApplicationSingle Use Processing
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IndustryPharma / Biotech
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Modality
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Buffer & Auxiliaries Filtration
- Form & Fill
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Buffer & Auxiliaries Filtration
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ScaleProduct Development | Scale Up Filters
Biological Information
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Bacterial RetentionQuantitative Retention of 1 × E7 CFU/cm² Brevundimonas Diminuta ATCC® 19146 per ASTM methodology
Compliance Information
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Bacterial Endotoxins< 0.25 EU/mL as determined by the LAL test
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Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
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ExtractablesThe total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".
Connections (Physical)
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Connector Inlet1/4" Multiple Stepped Hose Barb
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Connector Outlet1/4" Multiple Stepped Hose Barb
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Connector(s)Inlet: ¼" Hose Barb | Outlet: ¼" Hose Barb
Dimensions
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Filter Sizesize 4 (0.021 m² / 0.22 ft²)
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Filtration Area0.021 m²
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Outer Diameter63 mm (46 mm without Connection / Valves)
General Specifications
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Capsule/Cartridge FormatCapsules
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Filter FormatCapsules
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Maximum Allowable Back Pressure2 bar (29 psi) at 20°C; 1.5 bar (21.8 psi) at 50°C
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Maximum Diffusion1.1 mL/min at 2.5 bar | 36 psi
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Minimum Required Bubble Point3.5 bar | 51 psi
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Vent ValveStandard
Materials of Construction
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Filter MaterialPolyethersulfone (PES)
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Housing MaterialPolypropylene (PP)
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Material o-ring | sealSilicone (SI)
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Membrane MaterialPolyethersulfone (PES)
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Support FleecePolypropylene (PP)
Operating Conditions
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Maximum Differential Pressure20 °C: 4 bar, 50 °C: 2 bar
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Maximum Operating Pressure4 bar (58 psi)
Physicochemical Information
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Non-Fiber ReleasingThis filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
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Pore Size Final-filter0.2 µm
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Pore Size Pre-filter0.45 µm
Product Information
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BrandSartopore® Platinum
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Pack Size5
Sterility/Purity
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Delivery ConditionNon sterile - Gamma irradiatable
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Sterilization MethodGamma Irradiatable
Usage Protocols
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Sterilization ProceduresGamma Irradiation: with 50 kGy, 1 Cycle