Sartobind® Rapid A

Sartobind^® Rapid A is a protein A membrane chromatography solution designed to increase the efficiency of antibody purification processes. This platform is well-suited for process intensification, reducing process times due to higher operational flow rates, while maintaining high binding capacities and minimizing back pressure. Altogether, Sartobind^® Rapid A has the potential to substantially reduce the cost associated with the mAb capture step, particularly in process development and production of material for early clinical phases.

Available formats:

• 96 Well Plates
• Capsules (1.2 mL, 10 mL, 75 mL and 200 mL)
• Cassette (0.8 L)

Complementary products:

• Rapid A Ligand
• Manifold Pilot Holder

Features and Benefits:

• Time Savings – faster cycling times with membranes mean less time is required for process development and validation. Moreover, column handling operations are no longer necessary.
• Cost reduction – especially for manufacturing of clinical phase material or smaller commercial scale
• Risk mitigation – because membranes are less sensitive to air presence or bed instability issues the risk of production stop is less significant
• Compact footprint and flexibility- smaller bed volumes can purify the same amounts of target molecules in the same amount of time. Furthermore, there is no need for ancillary equipment related to packing and maintenance.
• Scalability

Applications:

• Monoclonal antibody (mAb) purification
• Fc-region containing fusion proteins
• Bi-specifics, multi-specific antibodies