Sartobran® P | Mini Cartridge | 0.45µm | Size 7 | 5pc.

Tech Support Documents
Sartobran® P | Mini Cartridge | 0.45µm | Size 7 | 5pc.
 

  • Effective Filtration Area: 0.05 m² | 0.54 ft²
  • Pore Size: 0.65 µm prefilter | 0.45 µm final filter
  • Membrane Material: Cellulose Acetate
  • Sterilization: In-line steamable | Autoclavable
  • Adapter: Bayonet
  • O-ring material: Silicone

Type
Item No.: 
5231506D7------B
Discontinued
Pieces
5

Choose your Sartobran® P

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Sartobran® P with its unique low-binding cellulose acetate (CA) membrane is mainly used for the sterile filtration of blood & plasma products and vaccines. The ultra-low binding of the membrane material leads to highest product yield and exceptional filtration performance. Especially large, shear-stress sensitive proteins do not lose their structure and function when filtered through this special membrane. This will improve your product yield even further.

Main Applications

  • Coagulation factors, Albumin, lgG
  • Bacterial, viral & mRNA-based vaccines
  • Bioprocessed pharmaceuticals
  • Ophthalmics
  • Purified protein solutions
  • Biological fluids
  • Fluids containing preservatives

Membrane

Sartobran® P uses a double membrane made of Cellulose Acetate

Compatibility

Sartopore®2 Cartridges have been developed for sterilization using either autoclaving or in-line-steaming. The Cellulose Acetate membrane is compatible within a pH range of 4 to 8, which makes the Sartobran® P filters ideal for most of the relevant biopharmaceutical applications.

Cost savings:

By using single-use filter elements, there is no need to invest in stainless steel filter housings. Additional costs for cleaning the housing and cleaning validation are eliminated.

Flexibility

Sartobran® P filters are available in different sizes and formats with corresponding filter areas from 4.5 cm² up to 1.8 m². Different connections allow easy integration into existing systems.

Scale Up:

Consistent and predictable scale-up and scale-down procedures can be performed safely because all Sartobran® P filter elements are manufactured with the same membrane type and construction materials.

Quality:

Every single element is tested for integrity to meet the highest quality requirements.

Documentation:

Sartobran® P filters have been designed, developed and produced in accordance with the ISO 9001 certified quality management system. A validation manual is available in accordance with regulatory requirements.

Applications

  • Application
    • Blood and Plasma  
    • Vaccine Production  
  • Industry
    Pharma / Biotech  
  • Modality
    • Harvest | Cell Removal  
    • Downstream Intermediates  
    • Form & Fill  

Compliance Information

  • Bacterial Endotoxins
    < 0.25 EU/mL as determined by the LAL test  
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).  
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".  

Connections (Physical)

  • Connector Inlet
    Bayonet Adapter with O-ring (15)  

Dimensions

  • Filter Size
    size 7 (0.05 m² / 0.54 ft²)  
  • Filtration Area
    0.05 m² / 0.54 ft²  
  • Outer Diameter
    56 mm  

General Specifications

  • Capsule/Cartridge Format
    Mini Cartridges  
  • Maximum Allowable Back Pressure
    2 bar (29 psi) at 20°C; 1 bar (14.5 psi) at 80°C  
  • Maximum Diffusion
    3 mL/min at 1.5 bar | 22 psi  
  • Minimum Required Bubble Point
    2.0 bar | 29 psi  
  • Vent Valve
    N/A  

Materials of Construction

  • Housing Material
    Polypropylene (PP)  
  • Material o-ring | seal
    Silicone (SI)  
  • Membrane Material
    Cellulose Acetate (CA)  
  • Support Fleece
    Polypropylene (PP)  

Operating Conditions

  • Maximum Differential Pressure
    20 °C: 5 bar, 80 °C: 2 bar  
  • Maximum Operating Pressure
    5 bar (72.5 psi)  

Physicochemical Information

  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.  
  • Pore Size Final-filter
    0.45μm  
  • Pore Size Pre-filter
    0.65μm  

Product Information

  • Brand
    Sartobran®  
  • Pack Size
    5  
  • Type
    Mini Cartridge | Size 7  

Sterility/Purity

  • Delivery Condition
    Non sterile - Autoclavable | Steamable  
  • Sterilization Method
    Autoclavable & In-Line Steam Sterilizable  

Usage Protocols

  • Sterilization Procedures
    • In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles  
    • Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles  
  • Liquid Filter Housings
    Liquid Filter Housings
    Item no.
    M_Liquid_Filter_Housings

    Sartorius Stedim Biotech Sanitary Single Round Filter Housings are specifically designed for liquid filtration applications of the Bio-Pharmaceutical Industry. Application: bioreactors, CIP skids, autoclaves, lyophilizers and process tanks.

  • Sartocheck® 5 Plus Filter Tester
    Sartocheck® 5 Plus Filter Tester
    Item no.
    26787---FT---P

    The Sartocheck® 5 Plus Filter Tester is an automatic filter integrity tester with automated Quality Risk Management (QRM) designed to cover the complete range of integrity testing from small syringe filters up to large multi-round housings and tangential flow cassettes.

  • Sartocheck® 5 Filter Tester
    Sartocheck® 5 Filter Tester
    Item no.
    26787---FT

    The Sartocheck® 5 Filter Tester is an automatic filter integrity tester designed to cover the complete range of integrity testing from small syringe filters up to large multiround housings and tangential flow cassettes.

  • Sartoclean®
    Sartoclean®
    Item no.
    M_Sartoclean

    Sartoclean® family is a cellulose acetate (CA) membrane based prefilter. These filters are optimized for the protection of downstream equipment and Sartobran® cellulose acetate final filters.