Flexsafe STR®

Flexsafe STR® bags ensure excellent and reproducible growth behavior of the most sensitive production cell lines. The optimization of the resin formulation and the complete control of our raw materials, the extrusion process and the bag assembly guarantee a consistent lot-to-lot cell growth performance.

Reliable performance for essential processes

Standard Flexsafe STR® bag designs feature overlay and sparging aeration, multiple feed lines also with dip tubes and a redundant exhaust line. Gassing lines feature OPTA® SFT sterile connectors for the connection of the included filter transfer sets. Feed lines are made from weldable tubing and come with MPC quick coupling connectors. A bottom harvest line, a small volume sampling line and a temperature sensor sleeve are always included. For optimal process monitoring and control, we offer integrated single-use optical DO and pH sensors as well as an integrated single-use electrochemical pH probe. Sensor ports allow for the use of conventional multi-use probes for DO and pH measurement.

Adapt to every process

For more advanced processes such as intensified perfusion processes, our range of configured-to-order components offers unrivalled flexibility. Choose from advanced single-use PAT sensors such as BioPAT Viamass® for viable cell mass monitoring, add side ports for perfusion with ATF, or TFF systems and increase reliability through added sensor redundancy. Furthermore, tubing diameter on feed and gassing lines can be adjusted to fit process requirements. Connector options include OPTA® SFT sterile connectors, Aseptiquik®, and weldable tubing with MPC quick coupling connectors. Micro and Combi sparging enhance gas delivery and optional Rushton 6-blade impellers increase mixing performance. Reach out to your Sartorius representative to learn more on how Flexsafe STR® bags can be adapted to your process.

Ease-of-use

Flexsafe STR® bags are delivered ready-to-use including the necessary gassing line filters to get you started immediately. Installation of Flexsafe STR® bags is easy and straightforward, even more so with the electrical lifting device we offer for bioreactor volumes of 500L, 1000L and 2000L.

To reduce process risks, all bags come with a redundant exhaust line. An optional single-use exhaust cooler can be used in addition to the standard filter heater to further mitigate the risk of filter blocking.

Aseptiquik® and MPC quick coupling connectors are products of Colder Products Company®. Aseptiquik® is a registered trademark of Colder Products Company®.