CIMac™ Analytical Columns combine all elaborate characteristics of CIM® monoliths at analytical scale and are your perfect tool for analysis and control of manufacturing processes, ideal for process analytical technology (PAT).

Designed for fast and reproducible HPLC monitoring and quantitation of proteins, viruses, pDNA, and other large biomolecules, they allow you to achieve rapid, high-resolution and flow-independent separations in a matter of minutes.

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Products (23)

  • CIMac™ EDA 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.5116-1.3
    Ligand
    EDA (weak anion exchanger, ethylene diamine)
    Channel Size
    1.3 µm
    Bed Volume
    0.1 mL
  • CIMac™ QA 0.1 mL Analytical Column (6 µm)
    Item no.
    110.5113-6
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    6 µm
    Bed Volume
    0.1 mL
  • CIMac™ pDNA 0.3mL Analytical Column (1.4 µm)
    Item no.
    150.8501-1.4
    Ligand
    DEAE (weak anion exchanger, diethylamino)
    Channel Size
    1.4 µm
    Bed Volume
    0.3 mL
  • CIMac™ Adeno 0.1 mL Analytical Column (2 µm)
    Item no.
    110.8502-2
    Ligand
    QA modified for Adeno (strong anion exchanger, quaternary amine)
    Channel Size
    2 µm
    Bed Volume
    0.1 mL
  • CIMac™ EDA 0.1 mL Analytical Column (2 µm)
    Item no.
    110.5116-2
    Ligand
    EDA (weak anion exchanger, ethylene diamine)
    Channel Size
    2 µm
    Bed Volume
    0.1 mL
  • CIMac™ DEAE 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.5114-1.3
    Ligand
    DEAE (weak anion exchanger, diethylamino)
    Channel Size
    1.3 µm
    Bed Volume
    0.1 mL
  • CIMac™ r-Protein A 0.1 mL Analytical Column (2 µm)
    Item no.
    110.1004-2
    Ligand
    r-Protein A (affinity, recombinant protein A produced from E. Coli coupled to CDI-preactivated support)
    Channel Size
    2 µm
    Bed Volume
    0.1 mL
  • CIMac™ QA 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.5113-1.3
    Ligand
    QA (strong anion exchanger, quaternary amine)
    Channel Size
    1.3 µm
    Bed Volume
    0.1 mL
  • CIMac™ AAV full/empty 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.8503-1.3
    Ligand
    QA modified for AAV (strong anion exchanger, quaternary amine)
    Channel Size
    1.3 µm
    Bed Volume
    0.1 mL
  • CIMac™ SO3 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.6157-1.3
    Ligand
    SO3 (strong cation exchanger, sulfonate)
    Channel Size
    1.3 µm
    Bed Volume
    0.1 mL
  • CIMac™ r-Protein G 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.1011-1.3
    Ligand
    r-Protein G (affinity, recombinant protein G produced from E. Coli coupled to CDI preactivated support)
    Channel Size
    1.3 µm
    Bed Volume
    0.1 mL
  • CIMac™ SO3 0.1 mL Analytical Column (6 µm)
    Item no.
    110.6157-6
    Ligand
    SO3 (strong cation exchanger, sulfonate)
    Channel Size
    6 µm
    Bed Volume
    0,1 mL
  • CIMac™ OH 0.1 mL Analytical Column (6 µm)
    Item no.
    110.8140-6
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    6 µm
    Bed Volume
    0,1 mL
  • CIMac™ SO3 0.1 mL Analytical Column (2 µm)
    Item no.
    110.6157-2
    Ligand
    SO3 (strong cation exchanger, sulfonate)
    Channel Size
    2 µm
    Bed Volume
    0,1 mL
  • CIMac™ OH 0.1 mL Analytical Column (1.3 µm)
    Item no.
    110.8140-1.3
    Ligand
    OH (hydrophobic, hydroxyl)
    Channel Size
    1.3 µm
    Bed Volume
    0,1 mL
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    CIMac™ Analytical Columns are short-bed high-performance monolithic columns offering all the advantages of CIM® monolithic technology. Their small volume and short length enable high volumetric flow rates, allowing for the rapid acquisition of quantity and purity information within minutes.Hence, the CIMac™ Analytical Columns are ideal for the in-process and final control of various samples from different purification process steps.

    Features:

    • Volume of 0.1 mL (0.3 mL for CIMac™ pDNA)
    • Flow rates from 1 to 30 column volumes/minute (varies by type)
    • Application-optimized channel widths
    • Available in a wide variety of chemistries

    Benefits:

    • Analytical HPLC columns for nucleic acids, viral vectors, viruses, and other biomolecules
    • In-process analysis and quantitation, and final product
    • At-line monitoring and control of manufacturing processes (PAT)
    • Rapid, high-resolution analysis achieved in minutes
    • High sensitivity, accuracy and reproducibility
    • No sample carryover

    Product Information

    • Brand
      CIMac™