Sartobran® P | Cartridge | 0.45µm | 10" | Adapter 21

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Sartobran® P | Cartridge | 0.45µm | 10" | Adapter 21
 

Suitable for small to large-scale production, these cartridges feature low-adsorption cellulose acetate membranes for high recovery rates. They offer robust bioburden reduction and are compatible with in-line steam or autoclave sterilization.

Filter Size
Adapter
Item No.: 
5232106D1----P
Piece
1
*Custom/bulk order quotes are provided within 72 hours of request.
Sartobran® P | Cartridge | 0.45µm | 10" | Adapter 21
Sartobran® P | Cartridge | 0.45µm | 10

Suitable for small to large-scale production, these cartridges feature low-adsorption cellulose acetate membranes for high recovery rates. They offer robust bioburden reduction and are compatible with in-line steam or autoclave sterilization.

Item No.:
5232106D1----P
Number of pieces
1

Overview

Specifications

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Sartobran P 0.45 µm for Bioburden Reduction

Sartobran® P 0.45 µm filters provide bioburden and defined particle reduction for biopharmaceutical solutions, especially in vaccine and blood and plasma processes. The cellulose acetate membrane enables very low unspecific adsorption to support high product recovery and efficient processing.

Key Features

  • Cellulose Acetate Membrane: Very low unspecific adsorption supports high recovery of proteins and excipients, helping protect product yield.
  • Bioburden and Particle Reduction: Applied upstream to protect sterilizing-grade membrane filters and downstream equipment, improving process robustness.
  • Linear Scale-Up: Filtration areas from 4.5 cm² to 1.8 m² across different formats enable straightforward scaling from PD to production.
  • pH Compatibility: Operates within pH 4–8, covering a large portion of bioprocess fluids used in typical formulations.
  • Integrity and Compliance: Each element is integrity tested by bubble point and diffusion methods and manufactured under an ISO 9001 certified Quality Management System.
  • Sterilization Flexibility: Autoclavable and in-line steam sterilizable options (by format), with gamma-irradiatable variants available, support integration into existing SOPs.

Applications

  • Coagulation Factors, Albumin, IgG
  • Bacterial and Viral Vaccines
  • Bioprocessed pharmaceuticals
  • Intermediate and purified protein solutions
  • Biological fluids
  • Fluids containing preservatives

Benefits

  • High Product Recovery: Very low unspecific adsorption limits product binding and supports high yield in vaccine, plasma, and protein processes.
  • Efficient Processing: High throughput and reliable flow performance help shorten filtration cycles and streamline operations.
  • Downstream Protection: Upstream bioburden reduction helps protect sterilizing-grade filters and equipment, supporting consistent performance.
  • PFAS: Made without intentionally using PFAS compounds.

Accessories Information

  • Adapter
    Bottom: Open flat gasket | Top: Open flat gasket

Applications

  • Application
    • Blood and Plasma
    • Vaccine Production
  • Industry
    Pharma / Biotech
  • Modality
    • Harvest | Cell Removal
    • Downstream Intermediates
    • Form & Fill
  • Scale
    Production | Large Scale

Compliance Information

  • Bacterial Endotoxins
    < 0.25 EU/mL as determined by the LAL test
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filter Size
    10"(0.6 m² / 6.5 ft²)
  • Filtration Area
    0.6 m² / 6.5 ft²
  • Outer Diameter
    70 mm

General Specifications

  • Capsule/Cartridge Format
    Cartridges
  • Maximum Allowable Back Pressure
    2 bar (29 psi) at 20°C; 1 bar (14.5 psi) at 80°C
  • Maximum Diffusion
    15 mL/min at 1.5 bar | 22 psi
  • Minimum Required Bubble Point
    2.0 bar | 29 psi

Materials of Construction

  • Housing Material
    Polypropylene (PP)
  • Material o-ring | seal
    Silicone (SI)
  • Membrane Material
    Cellulose Acetate (CA)
  • Support Fleece
    Polypropylene (PP)

Operating Conditions

  • Maximum Differential Pressure
    20 °C: 5 bar, 80 °C: 2 bar
  • Maximum Operating Pressure
    5 bar (72.5 psi)

Physicochemical Information

  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
  • Pore Size Final-filter
    0.45 μm
  • Pore Size Pre-filter
    0.65 μm

Product Information

  • Brand
    Sartobran®
  • Pack Size
    1

Sterility/Purity

  • Delivery Condition
    Non sterile - Autoclavable | Steamable
  • Sterilization Method
    Autoclavable & In-Line Steam Sterilizable

Usage Protocols

  • Sterilization Procedures
    • In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles
    • Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles