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Chromatography (803)
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C4 HLD (hydrophobic, butyl – high ligand density)
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CIM®
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Screening, Gene therapy
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2μm
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0.2 mL
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QA HR (strong anion exchanger, quaternary amine)
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4,8 mm (Monolith)
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Gene therapy, Screening
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Clinical manufacturing, Commercial manufacturing
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Resolute®
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QA HR (strong anion exchanger, quaternary amine)
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CIM®
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Screening, Gene therapy
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2μm
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The PATfix® AAV Switcher Platform is a chromatography-based analytical platform that simplifies AAV quality monitoring with a 2-step process – capture and separation – to accurately measure viral quality from the complex upstream samples.
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PATfix® LNP Switcher is a chromatography-based analytical platform tailored for lipid nanoparticle (LNP) characterization, enabling at-line determination of encapsulation efficiency, particle size, and lipid composition to accelerate nucleic acid–based therapeutic development.
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PATfix® pDNA Platform: A chromatography-based analytical solution tailored for plasmid DNA (pDNA) processing, enabling rapid at-line isoforms (open circular, supercoiled, linear) and multimer separation, quantification, and process control across all stages.
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PATfix® mRNA Platform: A chromatography-based analytical platform tailored for mRNA characterization, enabling at-line IVT reaction monitoring, rapid quantification, and comprehensive quality control (size, integrity, dsRNA) to accelerate nucleic acid therapeutic development.
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Swiper (multimodal - anion exchange-hydrogen bonding)
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CIM®
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Screening, Gene therapy
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2μm
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PrimaT (multimodal - anion exchange-hydrogen bonding-metal affinity)
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CIM®
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Screening, Gene therapy
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2μm
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0.05 mL
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r-Protein G (affinity, recombinant protein G produced from E. Coli coupled to CDI preactivated support)
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2.5 mm (Monolith)
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Gene therapy, Screening
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When additional sample characterization is required, the fraction collector allows for easy automation of sample collection, that can then be analysed offline in-depth.
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