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Tangential Flow Filtration (TFF)
Single-use TFF Assemblies

Most used filters

Brand

Sartocon® (49)
Sartocube® (24)
Sartoflow® (21)

Cassette Format

Sartocon® SCU (23)
Sartocube® SCU (24)
Slice 50 Cassettes (20)
Slice Cassettes (24)

Filtration Area

0.14 m² (8)
0.28 m² (8)
0.42 m² (7)
1.4 m² (8)
3.5 m² (7)
7 m² (3)
7m² (1)
14 m² (4)
30 kDa (1)
50 cm² (22)
100 kDa (1)

MWCO

1 kD (1)
2 kD (1)
5 kD (2)
8 kD (1)
10 kD (4)
10 kDa (12)
30 kD (3)
30 kDa (12)
50 kD (2)
100 kD (2)
100 kDa (14)
300 kD (4)
300 kDa (12)

Membrane Material

Hydrosart® (38)
Polyethersulfone (PES) (32)

Sealing Compound

Not Applicable (22)
Silicone Grey (48)

Filter by product attributes

Additional Product Specifications

Conductivity sensor (1)
Flow sensor (1)
Integrated 5-piston single-use diaphragm pump head with integrated overpressure protection at 4 bar (18 L/min) (1)
Pressure sensor (2)
Temperature sensor (1)
UV sensor (1)

Application

Antibody Purification (21)
Buffer Exchange (21)
Concentration (20)
Desalting (21)
Diafiltration (7)
DNA Concentration (21)
Microfiltration (5)
mRNA concentration (4)
Protein Concentration (21)
Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins (21)
Single Use Processing (21)
Ultrafiltration (12)

Application Area

Buffer exchange (6)
Concentration (6)
Monoclonal antibody production (6)
Recombinant protein production (6)
Transferring (10)
Vaccines (6)

Bacterial Endotoxins

< 0.18 EU/mL as determined by the LAL test (56)
< 0.25 EU/mL as determined by the LAL test (8)

Connector Inlet

0.5" AseptiQuik® G (5)
1" Tri-clamp (2)
1-1/2" Tri-clamp (3)

Connector Outlet

0.5" AseptiQuik® G (5)
1" Tri-clamp (2)
1-1/2" Tri-clamp (3)

Connector(s)

AseptiQuik® G (1)
MPC (6)
MPC female 0.375" (1)
MPC female 0.5" (1)
Permeate: 0.25" AseptiQuik® G, MPC female 0.25" (1)
Retentate: 0.375" AseptiQuik® G, MPC female 0.375" (1)
Tri-clamp (6)
0.25" MPC male (1)
0.375" AseptiQuik® G (1)
0.5" AseptiQuik® G (6)
0.75" Tri-clamp (4)
1" Tri-clamp (2)
1-1/2" Tri-clamp (3)

Delivery Condition

Gamma irradiated (13)
Sterile (10)

Filter Configuration

Sartocon® ECO (30)
Sartocube Cassette (2)
Slice 50 Cassette (12)
Slice ECO Cassette (15)

Filter Format

Capsules (1)
Cassettes (69)

Flow Channel Geometry

Protein conc. <20% /or viscosity max.3cp (34)
Protein conc. >20% /or viscosity above.3cp (33)

Gamma Irradiation

Minimum dose of 25 kGy (10)
yes (4)

Inner Diameter

1" (6)
1/2" (4)

Maximum Inlet Pressure

3 bar (20)
4 bar (47)

Operating Pressure

Max. 4 bar | 58 psi (10)
4 bar (4)

Pack Size

1 (23)
2 (4)
3 (1)
5 (5)

pH Stability

pH 1 - 14 (20)
pH 1 – 14 (12)
pH 2 - 14 (28)
pH 2 – 14 (8)

Process Step

Buffer Preparation (10)
Cell Harvest & Downstream Processing Intermediates (10)
Clinical Trial Manufacturing (15)
Commercial Manufacturing (7)
Drug Product Formulation (10)
Drug Substance Purification (10)
Media Preparation (10)
Pilot (9)
Process Development (11)

Quality Standards

Components are compliant with EMA410/01 Rev3 requirements with regards to TSE | BSE (10)
Feature components tested for biocompatibility and certified according to USP<88 (10)
Manufactured according to a validated assembly process (10)
Manufactured in a controlled environment (Class 7 in operation according to ISO 14644) (10)
Supplied double-bagged and irradiated with a minimum dose of 25 kGy (10)
The quality management system is ISO 9001 compliant (10)

Tube Length

1500 mm (3)
3000 mm (3)
5000 mm (4)

Tube Size (ID – OD)

Permeate: 1/4" - 7/16" and 1/4" - 1/2" (1)
Retentate: 3/8" - 5/8" and 1/4" - 7/16" (1)
¼” (6.4 mm) (2)
1" × 1-3/8" (25.4 mm × 34.9 mm) (3)
1/2" - 3/4" (1)
1/2" × 3/4" (12.7 mm × 19.1 mm) (5)
1/4" - 7/16" (2)
3/4" × 1-1/8" (19.1 mm × 28.6 mm) (2)
3/8" - 5/8" (1)
3/8” (9.6 mm) (2)

Tube Type

Extension line (7)
Reinforced line (3)

Tubing

Braided Silicone (Tuflux® SIL Braided) (3)
Platinum cured silicone, reinforced in high pressure sections (4)
Platinum-cured silicone, reinforced in high-pressure sections (6)
Silicone (5)
TPE (C-Flex®) (2)

Tubing Material

Platinum-Cured Silicone (5)
Platinum-Cured Silicone with PET reinforcement (9)
Synthetic Thermoplastic Elastomer (2)

Type

Aseptiquik® (1)
Buffer & WFI (1)
Diafiltration (2)
E-Screen (High viscosity) (14)
ECO Screen (Low viscosity) (8)
Feed (4)
Media Transfer (1)
Permeate (2)
Permeate & Retentate (1)
Permeate 1/2 (1)
Permeate 2/2 UV (1)
Prefiltration (1)
Pump Head (1)
Retentate (3)
Tri-Clamp (1)
10L bag (1)
20L Bag (1)

Ultrafilter

1 kD Polyethersulfone Ultrafilter Membrane (1)
5 kD Polyethersulfone Ultrafilter Membrane (1)
8 kD Polyethersulfone Ultrafilter Membrane (1)
10 kD Polyethersulfone Ultrafilter Membrane (2)
30 kD Polyethersulfone Ultrafilter Membrane (2)
50 kD Polyethersulfone Ultrafilter Membrane (1)
100 kD Polyethersulfone Ultrafilter Membrane (2)
300 kD Polyethersulfone Ultrafilter Membrane (2)

Single-use TFF Assemblies (104)

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