Sartocon® and Sartocube® | TFF Microfiltration | Cassettes

Microfiltration TFF Cassette Solutions

Sartocon® and Sartocube® Microfiltration cassettes deliver high-performance separation combined with easy handling across various applications. Our cassette designs are self-sealing and feature enlarged feed and retentate ports for gentle product handling. They offer full scalability from development to large-scale manufacturing, thanks to consistent cassette geometry.

Membrane Types

• Hydrosart® membranes are stabilized cellulose derivatives with a broad pH and temperature range. They are hydrophilic, non-protein binding, and virtually non-fouling, supporting a consistently high flux
• Our polyethersulfone (PES) membrane offers high flux rates for fast processing, a stable polymer structure with a broad pH range (1–14) and good temperature tolerance, and minimal product loss thanks to its low-adsorptive material

Formats and Filtration Area

Sartorius TFF cassettes are available in multiple size formats.

• Sartocon® Slice 200 are ideal for reduced volume handling during development.
• Sartocon® Slice formats are optimal for small-scale production or small volume pilot runs.
• Sartocon® and Sartocube® are perfect for large-scale production

Accessories

• All microfiltration cassettes fit into Sartocon® and Sartoflow® holders for modular scale-up
• Wide range of Sartoflow® systems available to suit different process scales and requirements
• Configurations support flexible process development, optimization, and integration in manufacturing

Applications in Biopharmaceutical Processing

• Typical use cases include cell harvest, concentration and washing steps in upstream and downstream workflows.
• Hydrosart® microfiltration cassettes are used for mammalian cell harvest, bacteria, yeast removal, etc.
• PES microfiltration cassettes support mammalian cell removal and reduction of mycoplasma, bacteria, etc.