Microfiltration TFF Cassette Solutions
Sartocon® and Sartocube® Microfiltration cassettes deliver high-performance separation combined with easy handling across various applications. Our cassette designs are self-sealing and feature enlarged feed and retentate ports for gentle product handling. They offer full scalability from development to large-scale manufacturing, thanks to consistent cassette geometry.
Membrane Types
- Hydrosart® membranes are stabilized cellulose derivatives with a broad pH and temperature range. They are hydrophilic, non-protein binding, and virtually non-fouling, supporting a consistently high flux
- Our polyethersulfone (PES) membrane offers high flux rates for fast processing, a stable polymer structure with a broad pH range (1–14) and good temperature tolerance, and minimal product loss thanks to its low-adsorptive material
Formats and Filtration Area
Sartorius TFF cassettes are available in multiple size formats.
- Sartocon® Slice 200 are ideal for reduced volume handling during development.
- Sartocon® Slice formats are optimal for small-scale production or small volume pilot runs.
- Sartocon® and Sartocube® are perfect for large-scale production
Accessories
- All microfiltration cassettes fit into Sartocon® and Sartoflow® holders for modular scale-up
- Wide range of Sartoflow® systems available to suit different process scales and requirements
- Configurations support flexible process development, optimization, and integration in manufacturing
Applications in Biopharmaceutical Processing
- Typical use cases include cell harvest, concentration and washing steps in upstream and downstream workflows.
- Hydrosart® microfiltration cassettes are used for mammalian cell harvest, bacteria, yeast removal, etc.
- PES microfiltration cassettes support mammalian cell removal and reduction of mycoplasma, bacteria, etc.