The high capacity virus filter for robust and efficient removal of small non-enveloped and large enveloped viruses in blood & plasma applications.

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Products (5)

  • Virosart® HC Midicaps® Size 9
    Item no.
    5395328V9--FF--V
    Filter Format
    Filter Capsules
    Filtration Area
    0.27 m² | 2.9 ft²
    Integrity Tested
    Yes
  • Virosart® HC Capsule Size 4
    Item no.
    5391328V4--FF--B
    Filter Format
    Filter Capsules
    Filtration Area
    240 cm² | 0.27 ft²
    Integrity Tested
    Yes
  • Virosart® HC Standard Filter Cartridge
  • Virosart® HC Minisart®
  • Virosart® HC T-Style Maxicaps®
  • Application:

    • Virus clearance: Virosart® HC retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV).
    • Target molecule: The main applications for Virosart® HC for virus filtration are hydrophobic feed streams such as IVIG or any other plasma derivates as well as hydrophobic antibodies & recombinant proteins (< 150 kD).
    • Positioning: Virosart® HC is used towards the end of the purification process of biopharmaceutical products for the virus filtration. At this stage, the purity of the biopharmaceutical product is at its highest and so fouling of the filter by contaminants (DNA, CHOP, aggregates & lipoproteins) will be low.

    Product Benefits:

    • Robust virus clearance: Virosart® HC retains ≥ 4 LRV of small non-enveloped viruses (e.g. PPV, MVM) and ≥ 6 LRV of large enveloped viruses (e.g. MuLV). This filter offers highest virus safety over the entire flow decay profile independently of operating pressure.
    • Smart process transfer: Flexibility is give by using either cartridges in existing stainless steel housings or disposable capsules.
    • Ease of use: Virosart® HC are tested for integrity using a water-based diffusion test, e.g. based on the Sartocheck® technology of Sartorius Stedim Biotech

    Regulatory Compliance:

    • Each individual filter is tested for integrity
    • Validated for ≥ 4 LRV removal of small non-enveloped viruses using bacteriophage PP7
    • Designed, developed and manufactured in accordance with an
    • ISO 9001 certified Quality Management System
    • Meet or exceed the requirements for WFI quality standards set by the current USP
    • Non pyrogenic according to USP Bacterial Endotoxins
    • USP Plastic Class Test VI

    Product Information

    • Brand
      Virosart® HC  
  • MaxiCaps® T-Style Holder
    Item no.
    5ZGI--0008

    The Sartorius Stedim Biotech MaxiCaps® holder has been specially designed to integrate MaxiCaps® into biopharmaceutical processes.

  • Single round Housing T-Type
    Item no.
    7S12LEN00147

    Sartorius Stedim Biotech Sanitary Single Round Filter Housings are specifically designed for liquid filtration applications of the Bio-Pharmaceutical Industry. Application: bioreactors, CIP skids, autoclaves, lyophilizers and process tanks.

  • Single round Housing T-Type
    Item no.
    7S11LEN00091

    Sartorius Stedim Biotech Sanitary Single Round Filter Housings are specifically designed for liquid filtration applications of the Bio-Pharmaceutical Industry. Application: bioreactors, CIP skids, autoclaves, lyophilizers and process tanks.

  • MidiCaps® Holder
    Item no.
    5ZGLG-0007

    The Sartorius Stedim Biotech MidiCaps® holder has been specially designed to integrate MidiCaps® into biopharmaceutical processes.

  • Sartocheck® 5 Plus Filter Tester
    Item no.
    26787---FT---P

    The Sartocheck® 5 Plus Filter Tester is an automatic filter integrity tester with automated Quality Risk Management (QRM) designed to cover the complete range of integrity testing from small syringe filters up to large multi-round housings and tangential flow cassettes.

  • Virosart® Max
    Item no.
    M_Virosart_Max

    Maximize your virus filter performance with adsorptive pre-filtration. Virosart® Max is a specifically optimized virus pre-filter significantly increasing downstream virus filter performance.