Vivaspin® 20 Centrifugal Concentrator Polyethersulfone, 48 pc

Top Features of Vivaspin® 20 Centrifugal Concentrator Polyethersulfone  

  • Avoids membrane fouling with crossflow technology for low-volume samples 
  • Increases process speed with a high flux design  
  • Adapts to your sample and available equipment with options for centrifugal or pressurized ultrafiltration
  • Simplifies retentate sample retrieval with the pipette friendly dead-stop pocket

Popular Applications for Vivaspin® 20 Centrifugal Concentrator Polyethersulfone   

  • Macromolecule concentration 
  • Desalting  
  • Buffer exchange 

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Vivaspin® 20 is recommended for 5 to 20 mL sample volumes and is compatible with swing bucket or fixed angle rotors accepting 50 mL centrifuge tubes. It features twin vertical membranes for unparalleled filtration speed. An integral low-volume dead-stop pocket enables more than 100-fold concentration factors while eliminating the risk of sample loss and simplifying retentate retrieval. Volume graduations on the housing allow ultrafiltration progress to be easily monitored.

For increased process flexibility, Vivaspin® 20 is available with a range of unique accessories. Diafiltration Cups enable continuous diafiltration, for rapid, single-step buffer exchange or sample desalting. In addition, the Air Pressure Controller and fittings allow for centrifuge-free ultrafiltration. Gas pressure ultrafiltration is ideal when an appropriate centrifuge is unavailable (e.g., in field-work applications), for processing single samples, or when handling sensitive samples (e.g., enveloped viruses). For even faster processing, gas pressure filtration can be combined with centrifugation. 'Pressure-fugation' is particularly useful for challenging samples such as serum, or when using a low process temperatures.


  • Application
    Macromolecule Concentration
  • Application Area
    • Concentration
    • Diafiltration
    • Desalting
    • Buffer exchange
  • Intended Use
    General Laboratory Use (GLU)
  • Market
    • BioPharma
    • Research

Compliance Information

  • Animal Components
  • Certification
    ISO 9001


  • Membrane Area
    6.0 cm²
  • Overall Length
    116 mm

Materials of Construction

  • Concentrator Body/Sleeve
    Polycarbonate (PC)
  • Concentrator Cap
    Polypropylene (PP)
  • Filtrate Vessel
    Polycarbonate (PC)
  • Membrane
    Polyethersulfone (PES)
  • Membrane Material
    Polyethersulfone (PES)

Physicochemical Information

  • MWCO
    10 kDa

Product Information

  • Brand
  • Device Type
    • Centrifugal
    • Gas Pressure
  • Pack Size
  • Sample Type
    • Macromolecule
    • Protein
    • Peptide
    • Nanoparticles
    • Virus
    • VLP
    • Viral Vector
    • Exosome
    • LNP
    • Nucleic Acid


  • Dead Stop Volume
    50 µL
  • Hold-up Volume
    < 20 µL
  • Maximum Capacity, Fixed Angle Rotor
    14 mL
  • Maximum Capacity, Swing Bucket Rotor
    20 mL
  • Volume Range
    5 – 20 mL
  • Volume with Pressure Head
    15 mL
  • Male Coupling for 4 mm Pneumatic Tubing


    Use in combination with the Air Pressure Controller (VCA002) and 4 mm pneumatic tubing.

  • Air Pressure Controller (APC)


    Use for pressurization of Vivaspin® 20 or 100 centrifugal concentrators.

  • Charge Valve for Pressure Head VCA200


    Use in combination with Vivaspin® 20 Pressure Head (VCA200) and 4 mm pneumatic tubing.

  • Replacement 4 mm Pneumatic Tubing for VCA002


    Use in combination with Air Pressure Controller (VCA002) for pressurized operation of Vivaspin® 20|100.

  • Vivaspin® 20 Pressure Head


    Use in combination with Vivaspin® 20, Charge Valve (VCA005) and Air Pressure Controller (VCA002).

  • Vivaspin® 20 Diafiltration Cups, 12pc

    Top Features of Vivaspin® 20 Diafiltration Cups

    • Eliminate process steps with continuous diafiltration
    • Minimize buffer consumption by achieving 98% salt removal in a single spin

    Popular Applications for Vivaspin® 20 Diafiltration Cups

    • Salt or detergent removal
    • Buffer exchange
    • Sample pH adjustment
    • Low-molecular weight contaminant removal
    • Addition of preservatives, inhibitors or cofactors

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