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TFF Systems (14)
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Tangential Flow Filtration (TFF) SystemsProduct Family
TFF Systems - Process Solutions for Ultrafiltration and Diafiltration
Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.
The TFF portfolio can flex to accommodate individual requirements, with a range of options that include cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.Key Features
Availability of benchtop to production scale systems
Flow rate starting from 1 L/hr up to 5,000 L/hr depending on the system
Working membrane sizes from 50 cm² to 14 m² (optional up to 21 m²)
Single-use and multi-use
Highly- to fully automated
Compliancy to cGMP available -
Ambr® CrossflowProduct Family
Study factors for manufacturability
Collect important information about the behaviour of the molecules in downstream processing already in an early stageAutomated, parallel trials
Up to 16 channels can be managed by one control stationLowest process volumes
Small scale screening with 10 cm² membrane area | 5 mL recirculation volumeFlexibility of two different process scales
Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area
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Sartoflow®
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Ultrafiltration, Diafiltration
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Slice Cassettes, Slice 50 Cassettes, Slice 200 Cassettes, Standard Cassettes
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1.5 - 3 L (SU)
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Sartoflow®
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Ultrafiltration, Diafiltration, Microfiltration
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Sartocon Cassettes, Slice Cassettes, Standard Cassettes
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5, 10, 20 L (SU)
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Sartoflow®
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Ultrafiltration, Diafiltration, Microfiltration
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Software: Biobrain® Recipe tool
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Tri-clamp, AseptiQuik® Connector
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Ambr® crossflow, Sartoflow®
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Concentration, Microfiltration, Ultrafiltration, Desalting, Buffer Exchange, Single Use Processing, Antibody Purification, Protein Concentration, DNA Concentration, mRNA concentration, Conjugation, ADC
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Sartocon® SCU, Sartocube® SCU, Sartocon Cassettes, Sartocube Cassettes
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1-20 L (20 L 3D mixing bag)
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Ambr® crossflow
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4
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Diafiltration, Ultrafiltration
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620 × 600 × 540 mm (4 channel module)
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