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TFF Systems (13)
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Sartoflow® Tangential Flow Filtration SystemsProduct FamilySartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.
The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.
Benchtop to production scale from 100 mL to 200 L
Working membrane sizes from 10 cm² to 10 m²
Single-use and multi-use
Highly- to fully automated
Compliancy to cGMP available
Modular standard systems allow shorter lead times -
Ambr® CrossflowProduct FamilyStudy factors for manufacturability
Collect important information about the behaviour of the molecules in downstream processing already in an early stage
Automated, parallel trials
Up to 16 channels can be managed by one control station
Lowest process volumes
Small scale screening with 10 cm² membrane area | 5 mL recirculation volume
Flexibility of two different process scales
Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Concentration, DNA Concentration, Antibody Purification, Desalting, Buffer Exchange, Protein Concentration, Single Use Processing
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Slice Cassettes, Slice 50 Cassettes, Standard Cassettes
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602 × 440 × 610 mm
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
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Cassettes
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Sartoflow®
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Concentration, Microfiltration, Ultrafiltration, Desalting, Buffer Exchange, Single Use Processing, Antibody Purification, Protein Concentration, DNA Concentration, mRNA concentration
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Sartocon® SCU, Sartocube® SCU, Sartocon Cassettes, Sartocube Cassettes
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1-20 L (20 L 3D mixing bag)
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Sartoflow®
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins
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Sartocon Cassettes, Slice Cassettes, Standard Cassettes
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0.5" Tri-clamp
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