Ksep® 400 System

Patented Ksep® systems technology is the only current technology that provides significant advantages for users that want to either harvest cells as product or discard cells as by-product during manufacturing.

Benefits

Smart Bioprocessing

• Integrates and | or reduces processing steps and time
• Improves recoveries of both solids and liquids
• Provides option to selectively remove small particulate impurities, e.g. plastic generated, cell debris
• Built-in scalability (4 – 6 fold) for development and manufacturing using the same system
• Automated with option to run in complete manual mode
• No hardware change for different applications
• Handles low to high cell density cultures (>150 million cells/mL) equally well

Advanced Cell Handling

• Imparts low shear on cells and keeps the cells intact
• Maintains a healthy environment to sustain cell viability
• Complete supernatant product recovery from slurry without dilution
• Reduces intracellular protein contamination for harvest applications by keeping the cells intact

Ensures cGMP Manufacturing

• Closed system with single-use class VI product contact surfaces
• Simple, robust, and scalable
• One software for all systems
• Clog-free and continuous operation

Applications

• Harvest | Clarification
• Cell Therapy
• Vaccine Manufacturing
• Blood Processing
• Learn more at www.sartorius.com/ksep-systems