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Moving from a chromatography skid to integrated downstream processing.
Enables batch, multiple multi-column processes (parallel batch, continuous) or multi-step integration resulting in Process Intensification.
Resolute® BioSC Pilot can operate simultaneously and continuously three chromatography separations, including viral inactivation and in-line buffer preparation.
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VeroProduct FamilyThe Vero cell line is used for various purposes, most importantly for the production of cell culture-based viral vaccines. Reasons for the extensive use of the Vero cell line are the consistent high viral yields and susceptibility to infect a mutiple range of viruses, as well as relatively easy adaptation for growth in bioreactors on microcarriers, thus allowing up-scaling without loss of cell productivity.
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The PATfix® AAV Switcher Platform is a chromatography-based analytical platform that simplifies AAV quality monitoring with a 2-step process – capture and separation – to accurately measure viral quality from the complex upstream samples.
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Item no.MWCO300 kDaMembrane MaterialHydrosart®Channel HeightECO Screen (Low viscosity)PriceItem no.MWCO300 kDaMembrane MaterialHydrosart®Channel HeightECO Screen (Low viscosity)Item no.MWCO300 kDaMembrane MaterialHydrosart®Channel HeightE-Screen (High viscosity)
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Item no.Volume50 LSurface FinishRa ≤ 48µinIntegrated WeighingNoJacket TypeJacketed ASMEPriceItem no.Volume50 LSurface FinishRa ≤ 48µinIntegrated WeighingNoJacket TypeJacketed ASMEItem no.Volume50 LSurface FinishRa ≤ 48µinIntegrated WeighingYesJacket TypeJacketed ASME
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Sartoflow®
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Ultrafiltration, Diafiltration, Microfiltration
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1/2"
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5, 10, 20 L (SU)
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Tangential Flow Filtration (TFF) SystemsProduct Family
TFF Systems - Process Solutions for Ultrafiltration and Diafiltration
Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.
The TFF portfolio can flex to accommodate individual requirements, with a range of options that include cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.Key Features
Availability of benchtop to production scale systems
Flow rate starting from 1 L/hr up to 5,000 L/hr depending on the system
Working membrane sizes from 50 cm² to 14 m² (optional up to 21 m²)
Single-use and multi-use
Highly- to fully automated
Compliancy to cGMP available