Sartobran® P 0.2 and 0.45 µm filters feature cellulose acetate membranes for low adsorption and high product recovery. The 0.2 µm grade ensures sterilizing filtration, while the 0.45 µm grade excels in bioburden reduction. Scalable formats support diverse biopharmaceutical applications.

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Sartobran® P
Sartobran® P

Sartobran® P 0.2 and 0.45 µm filters feature cellulose acetate membranes for low adsorption and high product recovery. The 0.2 µm grade ensures sterilizing filtration, while the 0.45 µm grade excels in bioburden reduction. Scalable formats support diverse biopharmaceutical applications.

Item No.:
M_Sartobran_P

Overview

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Sartobran® P 0.2 and 0.45 µm filters

Sartobran® P filters combine cellulose acetate membranes with low adsorption to support high product recovery across vaccine, blood and plasma, and biopharmaceutical processes.

Key Features

  • Low-Adsorption Membrane: Cellulose acetate minimizes unspecific binding to help protect yield and support consistent recovery of valuable proteins and excipients.
  • Gentle To Proteins: Flow characteristics and membrane properties help maintain the structure of large, shear‑sensitive proteins for reliable process performance.
  • Two Retention Ratings: 0.2 µm for sterilizing-grade filtration and 0.45 µm for bioburden and particle reduction, enabling step-appropriate selection in upstream and final steps.
  • Scalable Portfolio: Sartoscales, Capsules, Midicaps®, Maxicaps®, and cartridges provide a common platform that supports linear scale-up from process development to commercial production.
  • Process Compatibility: Operates in the pH 4–8 range typical for many formulation buffers and process fluids, broadening applicability across unit operations.

Applications

  • Coagulation Factors, Albumin, IgG
  • Bacterial and Viral Vaccines
  • Bioprocessed pharmaceuticals
  • Intermediate and purified protein solutions
  • Biological fluids
  • Fluids containing preservatives

Benefits

  • High Product Recovery: Very low unspecific adsorption helps reduce product loss, supporting high yields in vaccines, blood and plasma, and biopharmaceutical processes.
  • Consistent Sterile Performance: The 0.2 µm grade is validated as sterilizing-grade and supports reliable bacterial retention in critical steps.
  • Efficient Bioburden Reduction: The 0.45 µm grade reduces bioburden and particles upstream to help protect final sterilizing filters and downstream equipment.
  • PFAS: Made without intentionally using PFAS compounds.

Applications

  • Application
    • Blood and Plasma
    • Vaccine Production
  • Modality
    • Harvest | Cell Removal
    • Downstream Intermediates
    • Form & Fill

Materials of Construction

  • Membrane Material
    Cellulose Acetate (CA)

Physicochemical Information

  • Pore Size Final-filter
    0.2 µm or 0.45 µm
  • Pore Size Pre-filter
    0.45 µm or 0.65 µm

Product Information

  • Brand
    Sartobran® P