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Manufacturing Scale Bioreactors (227)
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Biostat STR®Product FamilyBiostat STR® single-use bioreactors running on the Biobrain® automation platform offer multiple configurations and convenient software upgrades to quickly adapt facilities as requirements change. The generation 3 system is now available with integrated Repligen XCell ATF® Technology for intensified processes and access to our best-in-class BioPAT® toolbox. Biostat STR® bioreactors and Flexsafe STR® bags range from 50 L to 2,000 L and can enhance speed, quality, and flexibility in process development and commercial manufacturing operations.
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Biostat STR® MicrobialProduct FamilyBiostat STR® Microbial is a high-performing single-use fermenter in the conventional stirred-tank design.The instrument is based on a synchronized concept of the three key elements, system hardware (bag holder and control tower), single-use vessel and automation platform.
The bag holder is housing and supporting the bag, with that delivering its functionality. While the control tower comes with a touch-screen HMI, it provides PAT as well as actuator interfaces.
The consumables are composed of the Flexsafe STR® bags and an advanced exhaust line ensuring highest performance and supporting robust microbial processes.
The unique control tower concept with Biobrain®
automation platform allows highest flexibility, easy configuration switch over and stand-alone GMP process supervision.
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Biostat® RMProduct FamilyThe Biostat® RM is a GMP compliant, wave-mixing bioreactor. It is paired with single-use Flexsafe® RM bags and is proven for a broad range of different cell lines incl. CHO, NS0, Sf9, E. coli, stem cells, and CAR-T cells. Especially, customers working with shear-stress-sensitive cell lines and bioconjugates acknowledge benefits of the rocking motion technology.
The modular concept of the Biostat® RM portfolio, ranging from 2 L to unique 200 L, provides flexibility to manage your individual process needs. Biostat® RM saves space, reduces costs, and increases yields. In addition, Biobrain® - the commercial manufacturing-ready automation platform shared between Biostat® RM and Biostat STR® - enables a seamless transfer from product development to manufacturing scale. This makes the Biostat® RM an integral part of the intensified seed train
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Flexsafe STR®Product FamilyFlexsafe STR® bags are to be used with Biostat STR® hardware. Together, they form our fully scalable single-use bioreactor based on a conventional stirred-tank design. Biostat STR® bioreactors and Flexsafe STR® bags range from 50 L to 2,000 L and can enhance speed, quality, and flexibility in process development and commercial manufacturing operations.
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Flexsafe® RMProduct FamilyThe bags are mainly clustered in Basic, Optical, Perfusion and RM TX bags. Some configurations include optical sensors, biomass sensor, screw caps or perfusion membrane.
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Mycap® CCX for Cell ExpansionProduct FamilyMycap® CCX Cell Expansion System turns standard Erlenmeyer flasks into closed, pump-ready culture vessels. Feed, inoculate and sample outside a laminar flow cabinet without ever removing the cap.
Gas-exchange cartridge keeps O₂/CO₂ in balance.
Integral tubing supports sterile fluid transfer.
Quickseal® for clean line removal.
Supplied ready to use on 125 - 3000 mL flasks. -
Univessel® SUProduct FamilyThe Univessel® SU is a single-use benchtop bioreactor vessel for mammalian cell culture applications during research and manufacturing. Dedicated vessel designs support specific process applications, including advanced operating modes and new modalities.
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Biostat® STR Generation 3
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Cell Culture
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BioPAT® Viamass, BioPAT® Trace, Optical DO, Optical pH, Temperature
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Cell therapies, mAB production, Recombinant protein production, Vaccine production
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Biostat® STR Generation 3
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Microbial Fermentation
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Optical pH, Optical DO, Temperature
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pDNA production, Recombinant protein production, Vaccine production
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Biostat® RM
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Cell Culture, Microbial Fermentation
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Optical pH, Optical DO, BioPAT® Viamass, BioPAT® Trace, Temperature
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Preclinical and clinical studies, Small scale production of monoclonal antibodies, Recombinant protein production, Vaccine production, Large scale seed expansion
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Item no.Connector(s)AseptiQuik® ConnectorType of SensorElectrochemical pH & Optical DO
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Item no.Connector(s)Opta® SFT ConnectorType of SensorElectrochemical pH & Optical DOPriceItem no.Connector(s)Opta® SFT ConnectorType of SensorElectrochemical pH & Optical DOItem no.Connector(s)AseptiQuik® ConnectorType of SensorElectrochemical pH, Optical DO & Probe Ports
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Item no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume2000 LPriceItem no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume2000 LItem no.Connector(s)Opta® SFT ConnectorType of SensorElectrochemical pH & Optical DOVolume500 LItem no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume50 L
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Item no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume500 LPriceItem no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume500 LItem no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume50 LItem no.Connector(s)Opta® SFT ConnectorType of SensorOptical pH & Optical DOVolume200 L
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