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Tangential Flow Filtration (TFF) (31)
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Tangential Flow Filtration (TFF) SystemsProduct Family
TFF Systems - Process Solutions for Ultrafiltration and Diafiltration
Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.
The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.Key Features
Availability of benchtop to production scale systems
Flow rate starting from 1 L/hr up to 5,000 L/hr depending on the system
Working membrane sizes from 50 cm² to 14 m² (optional up to 21 m²)
Single-use and multi-use
Highly- to fully automated
Compliancy to cGMP available -
Sartoflow® 150 SU Flow KitsProduct Family
The Sartoflow® 150 single-use TFF flow kit for use with the Sartoflow® 150 system:
Faster change-over between different products.
More efficient and productive system use.
Increased facility flexibility.
Increased productivity per sqm manufacturing space.Key Features of the System
Flexibility to run various types of TFF modules and cassettes.
Designed to generate scalable data for use in small-scale production and process development.
Reliable scale-up to larger scale SUTFF systems
Disclaimer: Please note that the Sartoflow® 150 system is discontinued and its successor is the Sartoflow® Expert Single-Use system. Sartoflow®150 flow kits remain available.
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Sartoflow® 4500 SU Flow KitsProduct Family
Key Facts
The Sartoflow® 4500 single-use flow kit is designed for the Sartoflow® 4500 TFF system.
Single-use design
Gamma irradiated
Controlled environment manufacturing
Quick installationBenefits
Fast turnaround: Quickly switch between products without extensive cleaning.
Reduced risk: Minimize contamination and product carryover.
Precise monitoring: Integrated sensors ensure accurate process control. -
Sartoflow® Expert Single-Use Flow KitsProduct Family
Sartoflow® Expert SU System with Precision-Engineered Flow Kits
Sartoflow® Expert flow kits are designed to enable the operational capabilities of the Sartoflow® Expert SU system. These flow kits play a crucial role in achieving optimal tangential flow filtration (TFF) performance.
Engineered for seamless integration, these single-use kits provide efficiency and reliability, ensuring that your processes are optimized for productivity and quality.Features & Benefits
Bioburden reduced
Chemical compatibility
Spill-free process and disassembly
Reduced hands-on time
No cleaning and validation effort -
Sartoflow® 1000 Single-Use Flow KitsProduct FamilyThe Sartoflow® 1000 single-use flow kit is designed specifically for the Sartoflow® 1000 system, these flow kits offer efficiency and safety in multi-product facilities.
Disclaimer: For more information on the system, please contact your local Sartorius representative.Features & Benefits of the Flow Kit:
Fast turnaround.
Reduced cleaning validation.
Minimized bioburden risk and product carryover in a multi-product facility.
Enhanced productivity. -
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Ultrafiltration, Diafiltration
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4 kg
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122.5 × 168.2 ×18.15 mm (single adapter )330.0 × 173.4 × 250.1 mm (stand with adapter)
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Ambr® Crossflow tubing, retentate vessel, sample pump and stirrer for one channel
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The system fluid kit for the Ambr® Crossflow contains:
Calibration buffer 1 (4 x 900 mL)
Calibration buffer 2 (4 x 900 mL)
Waste and System Bottle Kit
Air Filters Kit -
The pump head kit for the Ambr® Crossflow system contains:
Two spare pump heads -
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The Ambr® CF Waste, NaOH and Water Bottle Kit contains carboy heavy walled HDPE bottles including caps, breather and tubing assemblies for one Ambr® Crossflow system.
One Bottle Kit has:
1 x 4 L bottle
1 x 10 L bottle
1 x 20 L bottle -
The Ambr® Crossflow DF1, DF2 and Feed Bottle Kit contains:
2 x 500ml glass bottles with caps, breathers and tubing assemblies for one channel
1 x 100ml glass bottle with caps, breathers and tubing assemblies for one channel -
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Sartoflow®
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Concentration, Buffer exchange
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Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins, Concentration, DNA Concentration, Antibody Purification, Desalting, Buffer Exchange, Protein Concentration, Single Use Processing
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Tri-clamp
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