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Tangential Flow Filtration (TFF) (1109)
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Tangential Flow Filtration (TFF) SystemsProduct Family
TFF Systems - Process Solutions for Ultrafiltration and Diafiltration
Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials up to commercial production batches.
The TFF portfolio can flex to accommodate individual requirements, with a range of options that include cost-efficient multi-use systems or closed systems with single-use flow kits for bioburden reduced processing.Key Features
Availability of benchtop to production scale systems
Flow rate starting from 1 L/hr up to 5,000 L/hr depending on the system
Working membrane sizes from 50 cm² to 14 m² (optional up to 21 m²)
Single-use and multi-use
Highly- to fully automated
Compliancy to cGMP available -
Sartocon® and Sartocube® | TFF Ultrafiltration | CassettesProduct FamilySartorius TFF Ultrafiltration cassettes offer optimal solutions for UF/DF applications. Our two high-performance membranes — PES and Hydrosart® — both available in multiple cut-offs, ensuring the perfect fit for your process needs from lab to manufacturing scale.
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Sartocon® and Sartocube® | TFF Microfiltration | CassettesProduct Family
Membrane Materials: Hydrosart® or Polyethersulfone
Effective Filtration Areas: 0.02m² - 3m²
Pore Sizes: 0.1µm | 0.2µm | 0.45µm
Screen Types: Open Channes | Wide Spacer -
Ambr® CrossflowProduct Family
Study factors for manufacturability
Collect important information about the behaviour of the molecules in downstream processing already in an early stageAutomated, parallel trials
Up to 16 channels can be managed by one control stationLowest process volumes
Small scale screening with 10 cm² membrane area | 5 mL recirculation volumeFlexibility of two different process scales
Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area
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Sartocon® and Sartocube® | TFF Ultrafiltration | Self-ContainedProduct Family
Self-Contained Unit (SCU): Pre-flushed, sterile and ready to use
Cut-Offs: 10 - 300 kDa
Effective Filtration Areas: 0.14 - 14m²
Membrane Material: Hydrosart® or Polyethersulfone
Channel Design: ECO
Connectors: AseptiQuik®
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Tangential Flow Filtration (TFF) Filter HoldersProduct Family
Key Features of the TFF Filter Holders
Self-draining and self-venting thanks to vertical positioning
Large retentate channels for low pressure drop
Easy installation
Low hold-up volume
Monolithic design
All ports located on the product plate -
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Item no.MWCO10 kDaFiltration Area0.7 m²Channel HeightECO Screen (Low viscosity)PriceItem no.MWCO10 kDaFiltration Area0.7 m²Channel HeightECO Screen (Low viscosity)Item no.MWCO10 kDaFiltration Area0.14 m²Channel HeightECO Screen (Low viscosity)Item no.MWCO30 kDaFiltration Area0.14 m²Channel HeightECO Screen (Low viscosity)
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Item no.MWCO1 kDaFiltration Area0.7 m²Channel HeightE-Screen (High viscosity)Price
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Sartocon®
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Silicone Grey
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Slice Cassettes
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< 0.18 EU/mL as determined by the LAL test
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Item no.Cassette CapacitySartocon® Cassettes: ≤ 10Mirror InvertedNoConnectionsISOPriceItem no.Cassette CapacitySartocon® Cassettes: ≤ 10Mirror InvertedNoConnectionsISOItem no.Cassette CapacitySartocon® Cassettes: ≤ 10Mirror InvertedNoConnectionsDINItem no.Cassette CapacitySartocon® Cassettes: ≤ 10Mirror InvertedNoConnectionsZoll
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